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Streptokinase has no effect on Plasminogen. It acts upon by binding with Plasminogen to form a 1:1 composite & turns in a participating enzyme Plasmin. It is non-enzyme macromolecule acquired by certain strains of beta hemolytic streptococci. It resolve clot mainly by converting the intrinsic plasminogen present in the fibrin clot to its active agent form Plasmin. Streptokinase is called a Thrombolytic agent and acts best when it is given soon after the approach of heart attack symptoms. Streptokinase can also break up blood clots that form in intravenous tubes .
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